Golden-crusted Cajun chicken strips served alongside tender bowtie pasta smothered in a dreamy mozzarella cheese sauce—this is comfort food taken to the next level. Each bite delivers the perfect harmony of bold spices and silky creaminess, with the bowtie pasta acting as the ideal canvas to absorb all that flavor.

Whether you’re planning a cozy weeknight dinner or looking to impress at a gathering, this dish combines rustic warmth with restaurant-worthy appeal. From the smoky Cajun seasoning to the lush cheesy finish, it’s the kind of recipe that earns a spot in your regular rotation.

Why You’ll Love This Bowtie Pasta with Creamy Cajun Chicken and Mozzarella Cheese Sauce

Flavorful Fusion: Cajun spice blends beautifully with creamy cheese, delivering a robust, savory dish that never gets boring.
Quick but Impressive: Ready in under 45 minutes, this looks gourmet but is easy to pull off.
Hearty and Satisfying: The combination of protein-rich chicken and filling pasta makes this a one-plate meal.
Perfect for Any Occasion: Elegant enough for a dinner party, simple enough for busy weeknights.

Preparation Phase & Tools to Use

To bring this dish together smoothly, having the right tools makes all the difference:

Large Skillet or Cast Iron Pan: For searing the chicken to perfection, locking in moisture and creating that flavorful crust.
Large Pot: Essential for boiling the bowtie pasta evenly and quickly.
Whisk: Key for blending the cheese sauce into a silky consistency without lumps.
Tongs or Spatula: Helps in flipping the chicken and tossing the pasta gently with the sauce.
Cutting Board & Sharp Knife: For slicing the chicken breasts evenly to ensure even cooking.

With these basics in place, you’re all set to dive into one seriously mouthwatering recipe.

Ingredients for the Bowtie Pasta with Creamy Cajun Chicken and Mozzarella Cheese Sauce

Chicken Breast: Lean, protein-packed base that absorbs Cajun flavor beautifully.
Cajun Seasoning: Brings a smoky, spicy kick that elevates the dish.
Bowtie Pasta (Farfalle): Ideal for holding onto creamy sauces with its ridges and folds.
Mozzarella Cheese: Adds that melty, gooey element that creates the creamy sauce.
Heavy Cream: Provides a rich, silky texture to the sauce.
Garlic: Adds aromatic depth and flavor.
Butter: For cooking the chicken and adding richness to the sauce.
Olive Oil: Helps achieve a golden sear on the chicken.
Salt & Pepper: Balances the overall seasoning.
Parsley (optional): For a fresh and vibrant finish.

How To Make the Bowtie Pasta with Creamy Cajun Chicken and Mozzarella Cheese Sauce

Step 1: Season and Sear the Chicken

Pat the chicken breasts dry and season both sides generously with Cajun seasoning. Heat olive oil and butter in a skillet over medium-high heat. Sear chicken for 5–6 minutes on each side until golden brown and cooked through. Remove and let rest.

Step 2: Cook the Pasta

In a large pot, bring salted water to a boil and cook bowtie pasta according to package instructions. Drain and set aside.

Step 3: Make the Mozzarella Cheese Sauce

In the same skillet, add a touch more butter if needed. Sauté minced garlic for about 30 seconds, then pour in the heavy cream. Bring to a gentle simmer and whisk in shredded mozzarella until smooth and creamy. Add salt and pepper to taste.

Step 4: Combine and Slice

Slice the rested Cajun chicken into strips. Toss the cooked pasta into the mozzarella sauce, coating it thoroughly.

Step 5: Serve and Garnish

Plate the creamy pasta and top with sliced Cajun chicken. Garnish with fresh parsley and a sprinkle of extra mozzarella if desired.

Serving and Storing This Bowtie Pasta with Creamy Cajun Chicken

Serve this dish fresh off the skillet for maximum creaminess and flavor. It pairs wonderfully with garlic bread or a crisp green salad. If you have leftovers, store them in an airtight container in the refrigerator for up to 3 days.

To reheat, add a splash of milk or cream to a skillet and gently warm over low heat to revive the sauce without drying it out.

Frequently Asked Questions

How spicy is Cajun seasoning?

It has a moderate heat level. If you’re sensitive to spice, use less or mix with a milder seasoning.

Can I use a different pasta?

Absolutely. Penne, rigatoni, or rotini are great alternatives that hold the sauce well.

Can I make it ahead?

Yes, you can prepare the chicken and sauce in advance. Reheat with a splash of cream to restore creaminess.

Is it okay to use pre-shredded mozzarella?

You can, but freshly shredded melts smoother and creates a creamier sauce.

Can I add vegetables?

Yes! Spinach, mushrooms, or bell peppers add extra flavor and nutrition.

Want More Chicken Pasta Ideas?

If you love this Bowtie Pasta with Creamy Cajun Chicken and Mozzarella Cheese Sauce, you’ll want to check out these next:

Garlic Butter Chicken Balls with Creamy Parmesan Pasta for a cheesy and savory kick.
One Pot Creamy Tuscan Chicken Pasta for a sun-dried tomato twist.
Creamy Cajun Sausage Pasta if you love bold flavors and smoky depth.
Ultimate Cheesy Chicken Spaghetti when you crave layers of cheesy goodness.
Texas Roadhouse Style Garlic Butter Chicken Skillet for that restaurant-style satisfaction.

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Let me know in the comments if you tried this version or put your own twist on it. Did you add mushrooms or maybe switch the pasta? I love hearing your spins and swaps—let’s keep the kitchen creativity flowing!