When the smoky heat of Cajun spices meets the silky richness of garlic mozzarella sauce, magic happens. This Cajun Chicken Spaghetti in Creamy Garlic Mozzarella Sauce is the ultimate comfort food with a bold twist. Picture perfectly blackened chicken, juicy and flavorful, served over a luscious bed of spaghetti tossed in a decadent, creamy sauce that hugs every strand of pasta. It’s the kind of dish that turns any weeknight dinner into a special occasion.

The beauty of this recipe lies in the contrast—a crispy, spicy exterior on the chicken paired with a buttery, cheesy sauce that cools the heat just enough. It’s indulgent, but with a vibrant kick that keeps you going back for another bite. If you’re craving something hearty, flavorful, and incredibly satisfying, this one’s a guaranteed crowd-pleaser.

Why You’ll Love This Cajun Chicken Spaghetti in Creamy Garlic Mozzarella Sauce

This dish brings restaurant-quality flavor right to your kitchen, and it doesn’t require a culinary degree to pull off. It’s perfect for spice lovers who also appreciate the creamy comfort of a cheesy pasta sauce. The bold Cajun seasoning adds personality, while the creamy garlic mozzarella sauce creates an irresistible velvety finish. Plus, it’s a one-pan chicken and pasta wonder, ideal for busy evenings when you still want a homemade meal that feels like a treat.

Whether you’re serving guests or making a cozy dinner for two, this recipe has that “wow” factor without being fussy. It’s easy to customize, reheats beautifully, and delivers satisfaction with every forkful.

Preparation Phase & Tools to Use

To set yourself up for success, gather these essential tools before you begin:

Cast Iron or Nonstick Skillet: Perfect for getting that beautiful crust on your Cajun chicken without sticking or burning.
Large Pot: For boiling spaghetti to al dente perfection.
Tongs or Spatula: For flipping and removing the chicken cleanly.
Whisk: Helps you blend the garlic mozzarella sauce smoothly, avoiding lumps.
Cutting Board & Sharp Knife: To slice the cooked chicken into elegant strips.

Each of these tools plays a key role in building texture and flavor. The skillet ensures your chicken has that crave-worthy char, while the whisk is your secret to a smooth, creamy sauce. Having everything ready makes the process smoother and keeps the timing on point.

Ingredients for the Cajun Chicken Spaghetti in Creamy Garlic Mozzarella Sauce

Chicken Breasts: The protein star of the dish, these are seasoned and seared for maximum flavor and texture.
Spaghetti: Acts as the base to soak up all that creamy, spicy sauce.
Heavy Cream: Provides a rich, velvety texture to the garlic mozzarella sauce.
Mozzarella Cheese: Melts beautifully into the sauce, offering a stretchy, cheesy finish.
Parmesan Cheese: Adds sharpness and depth to balance the creaminess.
Garlic: Freshly minced garlic infuses the sauce with warm, aromatic flavor.
Butter: Enhances the richness of the sauce and helps cook the garlic gently.
Olive Oil: Used for searing the chicken to lock in moisture and flavor.
Cajun Seasoning: Brings the smoky, spicy flair that defines this dish.
Salt & Black Pepper: Essential for bringing all the flavors into focus.
Fresh Parsley (optional): Adds a fresh finish and a pop of color.

How To Make the Cajun Chicken Spaghetti in Creamy Garlic Mozzarella Sauce

Step 1: Season and Sear the Chicken

Pat your chicken breasts dry and coat them evenly with Cajun seasoning. Heat olive oil in a skillet over medium-high heat. Sear the chicken until golden brown and cooked through, about 4–5 minutes per side depending on thickness. Set aside to rest.

Step 2: Cook the Spaghetti

In a large pot, cook spaghetti in salted boiling water until al dente. Drain and set aside, reserving a bit of pasta water.

Step 3: Make the Garlic Mozzarella Sauce

In the same skillet, lower the heat and melt butter. Add minced garlic and sauté until fragrant. Pour in heavy cream and stir continuously. Slowly mix in mozzarella and parmesan until melted and creamy. If the sauce is too thick, add a splash of reserved pasta water.

Step 4: Toss Pasta in Sauce

Add the cooked spaghetti to the skillet and toss until well coated in the sauce. Make sure every strand gets covered.

Step 5: Slice and Serve the Chicken

Slice the seared chicken into strips and layer it over the creamy spaghetti. Garnish with chopped parsley and a pinch more Cajun seasoning if desired.

Serving and Storing Cajun Chicken Spaghetti

Serve this dish hot, straight from the skillet to the plate. It pairs beautifully with a simple side salad or garlic bread. If you’re serving a crowd, consider topping with extra mozzarella and placing it under the broiler for a minute to get a bubbly, golden finish.

Leftovers can be stored in an airtight container in the fridge for up to 3 days. To reheat, add a splash of milk or cream to loosen the sauce and microwave or warm on the stovetop. The flavors only deepen over time, making leftovers a treat.

Frequently Asked Questions

How spicy is Cajun chicken?

Cajun seasoning typically brings a medium level of heat with smoky, savory spices. You can adjust the spice level by using less seasoning or opting for a mild Cajun blend.

Can I use a different pasta?

Absolutely! Fettuccine, linguine, or even penne work well. Just make sure it holds onto the creamy sauce.

What if I don’t have heavy cream?

You can substitute with half-and-half or a mixture of milk and a bit of cream cheese, though the sauce will be slightly less rich.

Is this dish good for meal prep?

Yes! It reheats beautifully. Store the pasta and chicken separately if possible to maintain texture.

Can I make this gluten-free?

Yes. Use gluten-free spaghetti and check that your Cajun seasoning doesn’t include gluten-containing fillers.

Can I grill the chicken instead?

Definitely! Grilling adds extra smoky flavor and still delivers the Cajun kick.

Want More Pasta Dishes With a Kick?

If you loved this Cajun Chicken Spaghetti, here are some more flavor-packed meals you should try next:

Creamy Cajun Sausage Pasta for smoky sausage and a similar creamy finish.
Ultimate Cheesy Chicken Spaghetti with gooey comfort in every bite.
One Pot Smoky Chipotle Cheesy Chicken Pasta if you want bold, smoky, one-skillet magic.
Garlic Butter Chicken Balls with Parmesan Pasta for garlic lovers looking for a unique twist.
Bang Bang Chicken Recipe to satisfy your spicy cravings in a different form.

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And let me know in the comments how yours turned out. Did you dial up the heat? Try a different cheese blend? Did you serve it with garlic bread or go solo?

I love hearing how you make these recipes your own. Questions and tips are always welcome—let’s help each other cook with confidence.

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