This Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta is a bold, creamy, flavor-loaded dish that brings weeknight comfort food to new heights. Twisted rotini pasta captures every bit of the creamy Alfredo Velveeta and spicy Cajun beef, delivering richness in every bite. A hint of garlic weaves through the cheese sauce and the beef, pulling everything together in savory harmony.
Whether you’re looking to spice up your dinner routine or serve something memorable for guests, this dish delivers comfort and flair in one irresistible bowl. The creamy Alfredo blends perfectly with the zesty Cajun spice and hearty ground beef, while the garlic-tossed rotini makes every twirl of the fork worth savoring.
Why You’ll Love This Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
- Big Flavor: The Cajun seasoning kicks up the beef with bold heat, balanced beautifully by creamy Velveeta Alfredo.
- Crowd Favorite: Perfect for gatherings or family dinners, it’s satisfying, cheesy, and always goes fast.
- Quick Prep: With a few pantry staples and under 40 minutes, you’ll have a restaurant-style dish ready to devour.
- Versatile: Swap the beef for turkey or chicken, or add sautéed veggies to change it up.
- Leftover Magic: It reheats like a dream, making lunch the next day something to look forward to.
Preparation Phase & Tools to Use
Before jumping into cooking, gather your tools and prep the workspace to make this recipe go smoothly.
Essential Tools and Equipment:
- Large Skillet or Sauté Pan: This is where your Cajun-spiced ground beef will sizzle and build flavor.
- Large Pot: To boil your rotini pasta perfectly.
- Colander: For draining pasta without losing any of those spirals.
- Wooden Spoon or Spatula: Ideal for breaking up and browning the beef evenly.
- Mixing Bowl: Optional but handy if you want to combine cheese and pasta before adding beef.
- Grater (if using fresh garlic or topping with cheese): Adds freshness and flavor.
Each of these tools plays a role in streamlining your cooking, ensuring even cooking and reducing cleanup chaos.
Ingredients for the Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
- Rotini Pasta: The twists hold the creamy cheese sauce beautifully.
- Ground Beef: A hearty base, perfectly seasoned with Cajun spices.
- Cajun Seasoning: Adds smoky, spicy flavor that defines the dish.
- Velveeta Cheese (Alfredo Style): Brings a creamy, melty texture that’s the heart of the sauce.
- Heavy Cream: Helps smooth out the cheese and create a luscious sauce.
- Minced Garlic: Boosts the savory element and infuses each bite.
- Butter: For toasting garlic and building flavor in the sauce.
- Parsley (optional garnish): Adds a pop of color and freshness.
- Salt and Pepper: To taste, bringing balance to the rich, spicy profile.


How To Make the Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
Step 1: Boil the Pasta
Bring a large pot of salted water to a boil and cook the rotini according to package instructions until al dente. Drain and set aside.
Step 2: Brown the Beef with Cajun Heat
In a large skillet, add ground beef over medium heat. Break it up with a wooden spoon and cook until no longer pink. Sprinkle in Cajun seasoning and stir well. Cook for an additional 2 minutes to toast the spices.
Step 3: Garlic Butter Infusion
In a small saucepan or clean skillet, melt butter over medium heat. Add minced garlic and sauté until fragrant and slightly golden, about 1 minute.
Step 4: Build the Creamy Alfredo
Reduce heat to low. Add Velveeta Alfredo cubes to the garlic butter, followed by heavy cream. Stir continuously until cheese melts and sauce is smooth.
Step 5: Combine and Toss
Add cooked pasta to the cheese sauce and mix until well coated. Then fold in the Cajun ground beef. Toss until everything is fully combined.
Step 6: Garnish and Serve
Sprinkle with chopped parsley and a touch of shredded cheese if desired. Serve hot!
How to Serve and Store Cheesy Garlic Twisted Pasta
Serve this pasta dish straight from the skillet while it’s hot and melty. Pair it with a crisp green salad, garlic bread, or roasted veggies to complete the meal. For a spicy twist, drizzle with hot sauce or top with extra Cajun seasoning.
To Store: Let leftovers cool completely, then transfer them to an airtight container. Store in the fridge for up to 3 days. To reheat, simply microwave in short bursts or warm on the stove with a splash of cream or milk to bring back the creaminess.
Frequently Asked Questions
Can I use another type of pasta?
Absolutely! While rotini is ideal for holding sauce, penne, bowtie, or even elbow macaroni work great too.
Is Velveeta Alfredo the only cheese that works?
Not at all. If you don’t have Velveeta, substitute with cream cheese and shredded mozzarella or use a jarred Alfredo sauce in a pinch.
How spicy is this dish?
It depends on your Cajun seasoning. Some blends are milder, while others bring serious heat. Adjust to your taste or try a homemade version to control the spice.
Can I make this ahead of time?
Yes! Cook everything and store it in the fridge. Reheat before serving with a splash of cream to keep it smooth and creamy.
What protein substitutes can I try?
Ground turkey, chicken, or even plant-based crumbles all work well. Just be sure to season generously with Cajun spice.
Is it freezer-friendly?
You can freeze it, but the sauce might separate slightly on thawing. For best texture, enjoy fresh or within a few days of cooking.
Want More Cheesy Pasta Ideas?
If this creamy Cajun pasta has you craving more, check out these other savory and satisfying dishes:
- Garlic Butter Beef Cheesy Bowtie Pasta for a buttery twist with hearty beef.
- Ultimate Cheesy Chicken Spaghetti when you want a Southern classic with layers of flavor.
- Million Dollar Ravioli Casserole that’s rich, creamy, and baked to perfection.
- Creamy Cajun Sausage Pasta if you love heat with a smoky kick.
- Beef and Rotini in Garlic Parmesan Sauce for another easy and comforting skillet favorite.
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And let me know in the comments how yours turned out. Did you go heavy on the Cajun? Swap the beef for sausage or veggies?
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Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta
- Total Time: 35 minutes
- Yield: 4 servings
Description
This Cheesy Garlic Twisted Pasta with Cajun Ground Beef and Alfredo Velveeta recipe is the ultimate comfort meal—creamy, spicy, and loaded with flavor. Made with rotini pasta, Cajun-seasoned beef, Velveeta Alfredo, and garlic, this easy weeknight dinner is perfect for family meals or entertaining guests.
Ingredients
12 oz rotini pasta
1 lb ground beef
1 tablespoon Cajun seasoning (adjust to taste)
8 oz Velveeta cheese (Alfredo style), cubed
1/2 cup heavy cream
2 tablespoons butter
2 teaspoons minced garlic
1 tablespoon chopped parsley (optional garnish)
Salt and pepper to taste
Instructions
1. Bring a large pot of salted water to a boil. Cook rotini pasta according to package instructions until al dente. Drain and set aside.
2. In a large skillet over medium heat, add ground beef. Break it apart with a wooden spoon and cook until browned and no longer pink.
3. Sprinkle Cajun seasoning over the beef. Stir and cook for 2 more minutes to toast the spices.
4. In a separate skillet or saucepan, melt butter over medium heat. Add minced garlic and sauté until fragrant and golden (about 1 minute).
5. Lower the heat and add Velveeta cubes and heavy cream to the garlic butter. Stir constantly until cheese is melted and the sauce is smooth.
6. Add cooked rotini pasta to the Alfredo cheese sauce and stir until well coated.
7. Fold in the seasoned ground beef until everything is evenly combined.
8. Garnish with chopped parsley and a sprinkle of extra cheese, if desired. Serve hot.
Notes
To keep the sauce smooth when reheating, add a splash of milk or cream before microwaving.
You can adjust the heat level by using more or less Cajun seasoning or opting for a mild blend.
For a twist, substitute ground beef with sausage, chicken, or plant-based alternatives.
- Prep Time: 10 minutes
- Cook Time: 25 minutes
- Category: Pasta Dinner
- Method: Stovetop
- Cuisine: American
Nutrition
- Serving Size: 1¼ cups
- Calories: 610
- Sugar: 3g
- Sodium: 920mg
- Fat: 37g
- Saturated Fat: 17g
- Unsaturated Fat: 15g
- Trans Fat: 0.5g
- Carbohydrates: 42g
- Fiber: 2g
- Protein: 28g
- Cholesterol: 105mg
