Pasta lovers, prepare yourselves for a cozy, flavor-packed twist on your usual weeknight dinner. This Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce combines perfectly spiraled rotini pasta with a velvety cheese sauce, spicy Cajun beef, and gooey melted mozzarella. It’s hearty, bold, and comforting—exactly what you need when you want something indulgent yet easy.

This dish is loaded with personality: the creamy Velveeta coats each pasta twist beautifully, while the Cajun-spiced beef adds a smoky heat and a savory kick. Topped with melty mozzarella and just a hint of red chili and herbs, it’s the ultimate cheese-lover’s dream, ready to wow family or guests in under 40 minutes.

Why You’ll Love This Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce

Weeknight-Friendly: Quick to prepare and guaranteed to satisfy.
Ultimate Comfort: A cheesy, spicy bowl of pasta bliss.
Crowd-Pleaser: A family-style favorite that both kids and adults love.
Customizable: Dial up the spice or swap the beef for turkey or plant-based options.
Instagram-Worthy: Just look at that cheesy pull and vibrant color!

Preparation Phase & Tools to Use

Creating this dish is all about balancing textures and flavors—and having the right tools makes the process smoother:

Large Pot: Essential for boiling the rotini evenly. Rotini holds sauce well, and you want it cooked just to al dente.
Deep Skillet or Sauté Pan: Perfect for browning the ground beef and simmering it with Cajun spices.
Cheese Grater: Fresh mozzarella melts better and more evenly than pre-shredded.
Colander: To drain the pasta quickly without cooling it too much.
Mixing Spoon or Silicone Spatula: For folding the Velveeta sauce into the hot pasta and evenly distributing the beef.

With these tools and a few pantry staples, you’re on your way to cheesy pasta heaven.

Ingredients for the Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce

Rotini Pasta: Holds the cheese sauce well and gives a hearty texture.
Ground Beef: Adds richness and protein. Cajun-seasoned for a bold, spicy depth.
Cajun Seasoning: Brings the heat, smokiness, and signature Southern flavor.
Velveeta Cheese: The base of the sauce—melts to a creamy perfection.
Mozzarella Cheese: For that irresistible cheese pull and gooey top.
Heavy Cream or Milk: To smooth out the cheese sauce and add richness.
Red Chili Flakes (Optional): For extra heat.
Fresh Parsley: Adds color and freshness to the final presentation.
Olive Oil or Butter: For cooking the beef and enhancing flavor.
Salt and Pepper: For seasoning to taste.

How To Make the Creamy Mozzarella Rotini with Spicy Cajun Beef and Velveeta Sauce

Step 1: Cook the Rotini

Bring a large pot of salted water to a boil. Cook rotini according to package directions until al dente. Drain and set aside.

Step 2: Brown the Cajun Beef

Heat a skillet over medium-high heat. Add a splash of olive oil, then the ground beef. Break it apart as it browns. Sprinkle in Cajun seasoning and cook until fully browned and fragrant. Set aside.

Step 3: Make the Velveeta Sauce

In the same pot you used for the pasta, add cubed Velveeta cheese and a splash of cream. Stir constantly on low heat until the cheese is fully melted into a silky sauce.

Step 4: Combine Pasta and Sauce

Add the cooked rotini to the cheese sauce, stirring to coat every spiral. Then, fold in the Cajun beef mixture until evenly distributed.

Step 5: Top with Mozzarella

Transfer the mixture to a serving bowl or oven-safe dish. Sprinkle generously with shredded mozzarella and a pinch of chili flakes. Broil for 1-2 minutes (optional) to get that golden bubbly top.

Step 6: Garnish and Serve

Top with freshly chopped parsley and serve hot.

Serving and Storing Creamy Mozzarella Rotini with Spicy Cajun Beef

Serve It Hot and Fresh

This dish is best served immediately after cooking to enjoy the full melty-cheesy effect. Pair it with garlic bread or a simple green salad to round out the meal.

Storage Tips

Store any leftovers in an airtight container in the refrigerator for up to 3 days. Reheat in a microwave or stovetop with a splash of milk to loosen the sauce. Avoid freezing—the cheese sauce doesn’t hold up well.

Frequently Asked Questions

How spicy is this recipe?

The Cajun seasoning adds a medium heat level. Adjust by reducing or increasing the chili flakes to suit your spice tolerance.

Can I use a different type of pasta?

Yes, penne or macaroni are great alternatives. Choose shapes that hold onto sauce well.

Can I substitute Velveeta?

You can use a cheddar-mozzarella blend, but it won’t be as creamy as Velveeta. Add more cream or a bit of cream cheese to help.

What ground meat can I use instead of beef?

Ground turkey or chicken are both great substitutes. For a vegetarian option, try plant-based ground meat.

Can I make this ahead of time?

You can cook the beef and pasta separately and refrigerate them. Assemble and reheat with cheese sauce just before serving.

Want More Pasta Ideas with a Kick?

If you loved this Creamy Mozzarella Rotini, try out these bold and cheesy recipes next:

Garlic Butter Beef Cheesy Bowtie Pasta for another rich, beefy twist.
Ultimate Cheesy Chicken Spaghetti packed with creamy sauce and chicken.
Creamy Cajun Sausage Pasta for that Southern-inspired comfort.
Beef and Rotini in Garlic Parmesan Sauce if you prefer a milder but equally satisfying flavor.
One Skillet Spicy Honey BBQ Sausage Pasta when you’re craving sweet heat.

Save This Pin For Later

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time: Kitchen By Kate on Pinterest.

And let me know in the comments how yours turned out. Did you go all in on the spice or keep it mellow? Did you add any veggies?

I love hearing how others make these recipes their own. Questions are welcome too—let’s help each other cook smarter and tastier.