Comfort food doesn’t get more satisfying than this hearty, cheesy, and flavorful Cattle Drive Casserole. It’s the kind of dish that fills your kitchen with the savory aroma of seasoned beef, golden cornbread, and bubbling cheese. Whether you’re feeding a hungry family or prepping for a cozy potluck, this casserole promises to be a crowd favorite.

With a base of spiced ground beef, sweet corn, and tomatoes, layered under a fluffy cornbread topping and melted cheddar cheese, every bite offers the perfect balance of textures and tastes. It’s incredibly easy to throw together on a weeknight, yet comforting enough for a Sunday dinner.
What Kind of Cornbread Mix Works Best?
For the perfect fluffy and slightly sweet topping, use a cornbread mix like Jiffy. It combines well with the casserole’s savory bottom layer. If you prefer homemade, go for a batter that’s not overly sweet to balance the flavors. The cornbread layer not only adds heartiness but also soaks in all the beefy juices for added depth.
Ingredients for the Cattle Drive Casserole
Ground Beef
The main protein of the casserole, ground beef brings a rich and hearty flavor. Choose 85/15 for a good balance of fat and flavor.
Taco Seasoning
This gives the meat a Tex-Mex flair. You can use a store-bought packet or make your own with chili powder, cumin, paprika, and garlic powder.
Rotel Tomatoes
These canned tomatoes with green chilies provide tangy heat and moisture.
Corn Kernels
Sweet corn adds a pop of texture and balances the spiciness with natural sweetness.
Sour Cream
Used in the topping layer to make it creamy and help bind the cornbread.
Shredded Cheddar Cheese
A golden, melty finish that ties everything together with savory comfort.
Cornbread Mix
This is the key to the casserole’s signature topping. It rises beautifully and absorbs flavors from the beef layer.
Eggs & Milk
These are mixed with the cornbread to give it the right structure and lift.
Fresh Cilantro or Parsley (Optional)
Used as garnish for a pop of green and fresh finish.

How To Make the Cattle Drive Casserole
Step 1: Brown the Ground Beef
In a large skillet over medium heat, cook the ground beef until fully browned. Drain any excess fat, then add the taco seasoning and a splash of water. Stir until well coated and simmer for 2-3 minutes to meld the flavors.
Step 2: Add the Veggies
Mix in the Rotel tomatoes and drained corn. Let everything simmer together for another 5 minutes so the juices combine. Then, spread this beef mixture evenly into a greased 9×13-inch baking dish.
Step 3: Layer on the Sour Cream and Cheese
Spread an even layer of sour cream over the beef mixture. Then sprinkle 1 cup of shredded cheddar cheese across the top. This creamy, cheesy layer helps balance the heat and adds richness.
Step 4: Prepare the Cornbread Topping
In a medium bowl, combine the cornbread mix, milk, and eggs. Stir just until smooth, being careful not to overmix. Pour the batter evenly over the meat and cheese layer.
Step 5: Bake to Perfection
Preheat your oven to 350°F (175°C). Bake the casserole for 30-35 minutes, or until the cornbread is golden brown and a toothpick inserted comes out clean. The top should be set and slightly crispy.
Step 6: Garnish and Serve
Once baked, let the casserole cool for about 5 minutes. Top with fresh chopped cilantro or parsley and an extra dollop of sour cream if desired. Serve warm and enjoy every flavorful layer!
How to Serve and Store Cattle Drive Casserole
Cattle Drive Casserole is best served hot from the oven, with the cornbread top golden and the beef layer bubbling beneath. Pair it with a crisp green salad or a side of seasoned black beans for a full, satisfying meal. Add a dollop of sour cream or a splash of hot sauce on top for an extra flavor kick.
To store leftovers, let the casserole cool completely, then cover tightly with foil or transfer to an airtight container. It will keep well in the fridge for up to 4 days. To reheat, place a portion in the microwave or warm in the oven at 300°F until heated through. For longer storage, freeze individual servings for up to 2 months. Thaw overnight before reheating.
Frequently Asked Questions
Can I use ground turkey instead of ground beef?
Absolutely! Ground turkey is a great leaner option and still works beautifully with the taco seasoning and other ingredients.
What if I don’t have Rotel tomatoes?
You can substitute with canned diced tomatoes and a few spoonfuls of chopped green chilies to get a similar flavor.
Can I make this casserole ahead of time?
Yes, assemble everything except the cornbread topping. Cover and refrigerate. When ready to bake, prepare the topping fresh and pour it over the casserole before baking.
How do I make it spicier?
Add a pinch of cayenne to the beef mixture or use hot Rotel tomatoes. A few dashes of hot sauce in the meat mix also adds heat.
Is this recipe gluten-free?
Check your cornbread mix and taco seasoning—some do contain gluten. With gluten-free alternatives, this recipe can be easily adapted.
What cheese alternatives work well?
Monterey Jack or a spicy pepper jack cheese can replace cheddar for a zestier bite.
Want More Casserole Ideas?
If this Cattle Drive Casserole hit the spot, you might want to explore a few other warm and filling favorites from my kitchen:
- Try the Loaded Taco Beef Casserole if you’re craving bold spices and cheesy comfort.
- The Easy Lasagna Roll Ups are perfect when you want pasta night with a twist.
- For veggie-packed goodness, check out the Greek Phyllo Meat Pie, a flaky and flavorful dish.
- Our Cheesy Scalloped Potatoes also make a fantastic side or standalone comfort meal.
- And don’t miss the Crack Chicken Penne, creamy and full of flavor.
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And let me know in the comments how yours turned out. Did you go with cheddar or swap in pepper jack? Add an extra layer of veggies? I love seeing your spins on these recipes.
Questions or tips to share? Drop them below—let’s help each other cook smarter and cozier.


Cattle Drive Casserole
- Total Time: 45 minutes
- Yield: 6-8 servings
Description
A hearty, comforting Tex-Mex casserole layered with seasoned ground beef, sweet corn, tangy tomatoes, sour cream, melty cheddar, and golden cornbread topping. It’s the perfect all-in-one dish for family dinners, potlucks, or an easy meal prep night.
Ingredients
1 lb ground beef
1 packet taco seasoning
1 (10 oz) can Rotel tomatoes (with green chilies)
1 cup corn kernels (canned or frozen, drained)
1 cup sour cream
1 cup shredded cheddar cheese
1 (8.5 oz) box cornbread mix (like Jiffy)
2 large eggs
1/3 cup milk
Fresh cilantro or parsley for garnish (optional)
Instructions
- Preheat oven to 350°F (175°C) and grease a 9×13-inch baking dish.
- In a skillet, cook ground beef over medium heat until browned. Drain fat.
- Add taco seasoning and 1/4 cup water. Simmer for 2-3 minutes.
- Stir in Rotel tomatoes and corn. Simmer for another 5 minutes.
- Transfer meat mixture to baking dish and spread evenly.
- Layer sour cream over beef mixture, then sprinkle cheddar cheese.
- In a bowl, mix cornbread, eggs, and milk until smooth. Pour over the casserole.
- Bake for 30-35 minutes or until cornbread is golden and cooked through.
- Let cool for 5 minutes. Garnish with chopped cilantro or parsley.
- Prep Time: 10 minutes
- Cook Time: 35 minutes
- Category: Dinner
